| Identification | Back Directory | [Name]
lucanthone | [CAS]
479-50-5 | [Synonyms]
Lucantona
lucanthone
Lycanthone
Lucanthonum
Autophagy,inhibit,Lucanthone,Inhibitor
1-(2-diethylaminoethylamino)-4-(methyl)thioxanthen-9-one
1-[[2-(Diethylamino)ethyl]amino]-4-methyl-9H-thioxanthen-9-one
9H-Thioxanthen-9-one, 1-[[2-(diethylamino)ethyl]amino]-4-methyl- | [EINECS(EC#)]
207-532-4 | [Molecular Formula]
C20H24N2OS | [MDL Number]
MFCD00866726 | [MOL File]
479-50-5.mol | [Molecular Weight]
340.482 |
| Chemical Properties | Back Directory | [Melting point ]
64.5°C | [Boiling point ]
512.4±50.0 °C(Predicted) | [density ]
1.0915 (rough estimate) | [refractive index ]
1.5950 (estimate) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 25 mg/mL (73.43 mM) | [form ]
Solid | [pka]
10.00±0.25(Predicted) | [color ]
Off-white to orange |
| Safety Data | Back Directory | [Safety Profile]
Poison by intravenous
route. Human mutation data reported.
When heated to decomposition it emits very
toxic fumes of NOx and SOx. |
| Hazard Information | Back Directory | [Definition]
ChEBI: Lucanthone is a thioxanthen-9-one compound having a methyl substituent at the 1-position and a 2-[(diethylamino)ethyl]amino substituent at the 4-position. Formerly used for the treatment of schistosomiasis. It is a prodrug, being metabolised to hycanthone. It has a role as a schistosomicide drug, an antineoplastic agent, a photosensitizing agent, an EC 5.99.1.2 (DNA topoisomerase) inhibitor, an EC 5.99.1.3 [DNA topoisomerase (ATP-hydrolysing)] inhibitor, a prodrug, an adjuvant and a mutagen. |
|
| Company Name: |
Energy Chemical
|
| Telephone: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
cjbscvictory
|
| Telephone: |
13348960310 13348960310 |
| Website: |
www.weikeqi-biotech.com/ |
|