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479543-46-9

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479543-46-9 Structure

479543-46-9 Structure
IdentificationBack Directory
[Name]

VX-702
[CAS]

479543-46-9
[Synonyms]

CS-363
1-(5-CarbaMoyl-6-(2,4-difluorophenyl)pyridin-2-yl)-1-(2,6-difluorophenyl)urea
6-(N-carbamoyl-2,6-difluoroanilino)-2-(2,4-difluorophenyl)pyridine-3-carboxamide
[Molecular Formula]

C19H12F4N4O2
[MDL Number]

MFCD11616590
[MOL File]

479543-46-9.mol
[Molecular Weight]

404.322
Chemical PropertiesBack Directory
[storage temp. ]

Store at +4°C
Hazard InformationBack Directory
[Uses]

VX 702 is a p38 MAP kinase pathway inhibitor.
[Definition]

ChEBI: 6-(N-carbamoyl-2,6-difluoroanilino)-2-(2,4-difluorophenyl)-3-pyridinecarboxamide is a phenylpyridine.
[Biological Activity]

Orally active, ATP-competitive inhibitor of p38α MAPK; also inhibits p38β (K D values are 3.7 and 17 nM respectively).
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