ChemicalBook--->CAS DataBase List--->480-43-3

480-43-3

480-43-3 Structure

480-43-3 Structure
IdentificationBack Directory
[Name]

ISOSAKURANETIN
[CAS]

480-43-3
[Synonyms]

Citrifoliol
Kikokunetin
Isosakurametin
ISOSAKURANETIN
ISOSAKURANETIN(P)
ISOSAKURANETIN WITH HPLC
5,7-DIHYDROXY-4'-METHOXYFLAVANONE
4'-Methoxy-5,7-dihydroxyflavanone
(2S)-5,7-Dihydroxy-4'-methoxyflavanone
5,7-DIHYDROXY-4''-METHOXYFLAVANONE hplc
(2S)-5,7-dihydroxy-2-(4-methoxyphenyl)chroman-4-one
(2S)-5,7-dihydroxy-2-(4-methoxyphenyl)-2,3-dihydrochromen-4-one
(S)-2,3-dihydro-5,7-dihydroxy-2-(4-methoxyphenyl)-4-benzopyrone
2-(4-Methoxyphenyl)-5,7-dihydroxy-2,3-dihydro-4H-1-benzopyran-4-one
(S)-2,3-Dihydro-2-(4-methoxyphenyl)-5,7-dihydroxy-4H-1-benzopyran-4-one
(S)-2,3-Dihydro-5,7-dihydroxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
[EINECS(EC#)]

207-551-8
[Molecular Formula]

C16H14O5
[MDL Number]

MFCD00017313
[MOL File]

480-43-3.mol
[Molecular Weight]

286.28
Chemical PropertiesBack Directory
[Melting point ]

193-194°C
[Boiling point ]

539.2±50.0 °C(Predicted)
[density ]

1.370±0.06 g/cm3(Predicted)
[solubility ]

DMSO : 125 mg/mL (436.64 mM; Need ultrasonic and warming)
[form ]

powder
[pka]

7.50±0.40(Predicted)
[color ]

White
[LogP]

3.840 (est)
Hazard InformationBack Directory
[Definition]

ChEBI: A dihydroxyflavanone that is flavanone substituted by hydroxy groups at positions 5 and 7 and a methoxy group at position 4' (the 2S stereoisomer).
[Chemical Properties]

Yellow crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO. It comes from Prunus serrulata, a plant of the genus Prunus in the Rosaceae family.
[Uses]

(S)-Isosakuranetin, is a flavanone flavonoid which can be found in the fruit of Citrus bergamia.
[in vivo]

Isosakuranetin dose-dependently increases the paw-withdrawal threshold within the dose range of 1.5 to 6 mg/kg. Post hoc analysis reveals that Isosakuranetin increases the paw-withdrawal threshold and statistical significance is seen at times 30 and 40 min for the dose of 3 mg/kg and 30 to 60 min for the dose of 6 mg/kg[2].

[target]

ERK | PI3K | Akt | JNK | PKA | GSK-3 | Calcium Channel | Potassium Channel | Tyrosinase | TRPM3 | TRP1 | TRP2
Safety DataBack Directory
[Risk Statements ]

22
[Safety Statements ]

22-45
[HS Code ]

29329990
Spectrum DetailBack Directory
[Spectrum Detail]

ISOSAKURANETIN(480-43-3)1HNMR
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