ChemicalBook--->CAS DataBase List--->480-85-3

480-85-3

480-85-3 Structure

480-85-3 Structure
IdentificationBack Directory
[Name]

retronecine
[CAS]

480-85-3
[Synonyms]

Retronecin
(1R)-2,3,5,7aβ-Tetrahydro-1-hydroxy-1H-pyrrolizine-7-methanol
(1R)-2,3,5,7aβ-Tetrahydro-1α-hydroxy-1H-pyrrolizine-7-methanol
(1R,7aR)-2,3,5,7a-Tetrahydro-1-hydroxy-1H-pyrrolizine-7-methanol
(1R,7aR)-7-(Hydroxymethyl)-2,3,5,7a-tetrahydro-1H-pyrrolizin-1-ol
1H-Pyrrolizine-7-methanol, 2,3,5,7a-tetrahydro-1-hydroxy-, (1R,7aR)-
[Molecular Formula]

C8H13NO2
[MDL Number]

MFCD01684783
[MOL File]

480-85-3.mol
[Molecular Weight]

155.19
Chemical PropertiesBack Directory
[Melting point ]

119-120°
[alpha ]

20D +4.95° (c = 0.58 in alc)
[Boiling point ]

80 °C(Press: 0.01 Torr)
[density ]

1.29±0.1 g/cm3(Predicted)
[storage temp. ]

2-8°C
[solubility ]

Ethanol (Slightly), Methanol (Slightly)
[form ]

neat
[pka]

14.48±0.40(Predicted)
[color ]

Off-White to Light Brown
Safety DataBack Directory
[RIDADR ]

1544
[WGK Germany ]

3
[RTECS ]

VH7175000
[HazardClass ]

6.1(b)
[PackingGroup ]

III
[Hazardous Substances Data]

480-85-3(Hazardous Substances Data)
[Toxicity]

LD50 i.v. in mice: 634.0 ±26.0 mg/kg (Harris)
Hazard InformationBack Directory
[Uses]

(+)-Retronecine, is a Pyrrolizidine alkaloid (PA) , which is a hepatotoxic, that is, damaging to the liver. It is also tumorigenic. It can also be used as an intermediate for the synthesis of (+)-Lycopsamine (L487525), and (E325580).
[Definition]

ChEBI:Retronecine is a member of pyrrolizines.
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