| Identification | Back Directory | [Name]
cephaeline | [CAS]
483-17-0 | [Synonyms]
Cefalin
Cepheline
cephaeline
Aids002677
Alangine B
Aids-002677
Cephaelinel
(-)-Cephaelin
Desmethylemetine
Dihydropsychotrine
Isoquinoline alkaloid
Nsc32944 (dihydrochloride)
5853-29-2 (Dihydrochloride)
O-Phosphatidyl-ethanolamine
7',10,11-Trimethoxyemetan-6'-ol
(1R)-1-[[(2S,3R,11bS)-3-Ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-yl]methyl]-1,2,3,4-tetrahydro-7-methoxy-6-isoquinolinol | [EINECS(EC#)]
207-591-6 | [Molecular Formula]
C28H38N2O4 | [MDL Number]
MFCD14702530 | [MOL File]
483-17-0.mol | [Molecular Weight]
466.612 |
| Chemical Properties | Back Directory | [Appearance]
Crystalline Solid | [Melting point ]
115-1160C | [alpha ]
D20 -43.4° (c = 2 in chloroform) | [Boiling point ]
569.42°C (rough estimate) | [density ]
1.21±0.1 g/cm3 (20 ºC 760 Torr) | [refractive index ]
1.5800 (estimate) | [storage temp. ]
-20°C Freezer | [solubility ]
Acetonitrile: slightly soluble; Chloroform: slightly soluble; Ethanol: slightly soluble; Methanol: slightly soluble | [form ]
A crystalline solid | [pka]
9.90±0.40(Predicted) | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Chemical Properties]
Crystalline Solid | [Uses]
Has been used as an emetic and expectorant | [Definition]
ChEBI: A pyridoisoquinoline comprising emetam having a hydroxy group at the 6'-position and methoxy substituents at the 7'-, 10- and 11-positions. | [Health Hazard]
The toxicity of cephaeline is lower than thatof emetine. The toxic effects are cumula tive. Ingestion of high doses may producehypotension, muscle weakness, and gastroin testinal problems, including nausea, vomiting, and diarrhea. |
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