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483340-19-8

483340-19-8 Structure

483340-19-8 Structure
IdentificationBack Directory
[Name]

(αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1-butanoic Acid
[CAS]

483340-19-8
[Synonyms]

(αR
4-triazole-1-butanoic Acid
Isavuconazole interMediate 4
(αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1
(αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1-butanoic Acid
1H-1,2,4-Triazole-1-butanoic acid, β-(2,5-difluorophenyl)-β-hydroxy-α-methyl-, (αR,βR)-
(2R,3R)-3-(2,5-Difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanoic acid
(alphaR,betaR)-beta-(2,5-Difluorophenyl)-beta-hydroxy-alpha-methyl-1H-1,2,4-triazole-1-butanoic Acid
[Molecular Formula]

C13H13F2N3O3
[MDL Number]

MFCD28404610
[MOL File]

483340-19-8.mol
[Molecular Weight]

297.26
Chemical PropertiesBack Directory
[Melting point ]

191-193 °C(Solv: methanol (67-56-1))
[Boiling point ]

519.9±60.0 °C(Predicted)
[density ]

1.43±0.1 g/cm3(Predicted)
[storage temp. ]

Sealed in dry,Room Temperature
[solubility ]

DCM, Methanol
[pka]

3.89±0.23(Predicted)
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
Hazard InformationBack Directory
[Uses]

(αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-methyl-1H-1,2,4-triazole-1-butanoic Acid is an intermediate in the synthesis of Isavuconazole (I777830), an triazole based antifungal agent for the treatment of invasive fungal infections.
Spectrum DetailBack Directory
[Spectrum Detail]

(αR,βR)-β-(2,5-Difluorophenyl)-β-hydroxy-α-Methyl-1H-1,2,4-triazole-1-butanoic Acid(483340-19-8)1HNMR
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