| Identification | Back Directory | [Name]
S-adenosylmethionine | [CAS]
485-80-3 | [Synonyms]
13CH3-SAM
Methionine,active
S-ADENOSYLMETHIONINE
Adenosine Impurity 39
S-(5'-Adenosyl)methionine
MEFKEPWMEQBLKI-AIRLBKTGSA-O
S-adenosylmethionine USP/EP/BP
S-Adenosyl-L-methionine sulfate p-toluene sulfonate salt
5'-Adenosyl(methyl)(3-amino-4-oxo-4-hydroxybutyl)sulfonium
5'-[(3-Amino-3-carboxypropyl)methylsulfonio]-5'-deoxyadenosine | [Molecular Formula]
C15H23N6O5S | [MOL File]
485-80-3.mol | [Molecular Weight]
400.45 |
| Chemical Properties | Back Directory | [InChIKey]
QOWKLNSTGYYNGX-MDHPBGAINA-N | [SMILES]
C(O)(=O)[C@H](CCS(C[C@H]1O[C@@H](N2C3=C(C(=NC=N3)N)N=C2)[C@H](O)[C@@H]1O)C)N |&1:3,8,10,21,23,r| |
| Hazard Information | Back Directory | [Uses]
S-Adenosyl-methionine labelled-15N5 is a useful research chemical. CAS# 485-80-3 is used in ReFlexIn, flexible receptor protein-ligand docking scheme evaluated on HIV-1 protease. | [Definition]
ChEBI: S-adenosyl-L-methionine is a sulfonium compound that is the S-adenosyl derivative of L-methionine. It is an intermediate in the metabolic pathway of methionine. It has a role as a coenzyme, a nutraceutical, a micronutrient, a human metabolite, a Saccharomyces cerevisiae metabolite, a Mycoplasma genitalium metabolite and a cofactor. It is a conjugate acid of a S-adenosyl-L-methioninate. It is an enantiomer of a S-adenosyl-D-methionine. It is a tautomer of a S-adenosyl-L-methionine zwitterion. | [Synthesis]
S-adenosylmethionine is synthesized intracellularly from adenosine triphosphate (ATP) and methionine by methionine adenosyltransferase catalyzed by the loss of a methyl group to S-adenosylhomocysteine while participating in a methyl transfer reaction a | [Veterinary Drugs and Treatments]
In small animal medicine, SAMe is most commonly used as an adjunctive
treatment for liver disease (chronic hepatitis, hepatic lipidosis,
cholangiohepatitis, feline triad disease, etc.). It may also be of
benefit in osteoarthritis, treatment of acute hepatotoxin-induced
liver toxicity (e.g., acetaminophen toxicity), and at-risk patients on
long-term therapy using drugs with hepatotoxic potential.
In humans, SAMe is being used as a treatment for depression,
osteoarthritis, AIDS-related myopathy, intrahepatic cholestasis,
liver disease, alcoholic liver cirrhosis, fibromyalgia, adult ADHD,
Alzheimer’s, migraines, etc. |
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| Company Name: |
Rhawn Reagent
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| Tel: |
400-400-1332688 18019345275 |
| Website: |
http://www.rhawn.cn |
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