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488-16-4

488-16-4 Structure

488-16-4 Structure
IdentificationBack Directory
[Name]

2,3,4-TRIHYDROXYBUTANOICACID
[CAS]

488-16-4
[Synonyms]

(2R,3R)-2,3,4-TRIHYDROXYBUTANOIC ACID
Butanoic acid, 2,3,4-trihydroxy-, (2R,3R)-
[Molecular Formula]

C4H8O5
[MOL File]

488-16-4.mol
[Molecular Weight]

136.1
Chemical PropertiesBack Directory
[Boiling point ]

518.9±50.0 °C(Predicted)
[density ]

1.650±0.06 g/cm3(Predicted)
[storage temp. ]

2-8°C
[form ]

powder
[pka]

3.47±0.17(Predicted)
[color ]

white to off-white
[optical activity]

[α]/D 12.0±2.0°, c =1 in H2O
Hazard InformationBack Directory
[Uses]

(2R,3R)-2,3,4-Trihydroxybutanoic acid, also known as erythronic acid, is a naturally occurring organic acid found in the aqueous humor of the eye, as well as in urine, plasma, cerebrospinal fluid, and synovial fluid, prevalent in both healthy adults and children; it is produced through the oxidation of GlcNAc.
[Definition]

ChEBI: D-erythronic acid is an erythronic acid in which the stereocentres at positions 2 and 3 both have R-configuration (the D-enantiomer). It is a conjugate acid of a D-erythronate. It is an enantiomer of a L-erythronic acid.
[Biological Activity]

Erythronic acid is a sugar component of aqueous humour (eye). Erythronic acid is a normal organic acid present in a healthy adult and pediatric population and has been found in urineplasmaCSFaqueous humour (eye) and synovial fluid. Erythronic acid is formed when GlcNAc is oxidised.
[References]

[1] Polar emollients in cosmetic formulations enhance the penetration and biological effects of Phytosphingosine on skin
[2] Asymmetric synthesis of d-ribo-phytosphingosine from 1-tetradecyne and (4-methoxyphenoxy) acetaldehyde
[3] Rapid nanoscale quantitative analysis of plant sphingolipid long-chain bases by GC-MS
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