| Identification | Back Directory | [Name]
D-fructose 1,6-bis(dihydrogen phosphate) | [CAS]
488-69-7 | [Synonyms]
CPC 111 Esafosfan Fosfructose Diphosphofructose FOSFRUCTOSE TRISODIUM FRUCTOSE-1,6-DIPHOSPHAT 1,6 Fructose Diphosphate fructose-1,6-biphosphate Fructose-1,6-Bisphosphate Hexose diphosphate hydrate D-Fructose 1,6-bisphosphate Fructose Diphosphate Sodium Sodium fructose diphosphate 6-bis(dihydrogen phosphate) Fructose 1,6-diphosphate sodium Fructose 1,6-bisphosphate sodium D-Fructose 1,6-bisphosphoric acid D-FRUCTOSE 1,6-DIPHOSPHATE SODIUM D-Fructose 1,6-disphosphate sodium D-fructose 1,6-bis(dihydrogen phosphat beta-D-fructofuranose 1,6-bisphosphate alpha-D-fructofuranose 1,6-bisphosphate D-fructose 1,6-bis(dihydrogen phosphate) d-fructose 1,6-bisphosphate sodium salt hydrate d-[3-13C]fructose 1,6-bisphosphate(sodiuM salt) D-fructose 1,6-bis(dihydrogen phosphate) USP/EP/BP D(+)Fructofuranose 1,6-diphosphate Harden-Young ester [2,3,4-trihydroxy-5-(phosphonooxymethyl)oxolan-2-yl]methoxyphosphonic acid | [EINECS(EC#)]
207-683-6 | [Molecular Formula]
C6H14O12P2 | [MDL Number]
MFCD06794967 | [MOL File]
488-69-7.mol | [Molecular Weight]
340.12 |
| Chemical Properties | Back Directory | [Melting point ]
72--74°C | [Boiling point ]
819.8±75.0 °C(Predicted) | [density ]
2.007±0.06 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
Methanol (Slightly), Water (Slightly) | [form ]
Solid | [pka]
1?+-.0.10(Predicted) | [color ]
White to Off-White | [Stability:]
Hygroscopic | [InChI]
InChI=1S/C6H14O12P2/c7-3(1-17-19(11,12)13)5(9)6(10)4(8)2-18-20(14,15)16/h3,5-7,9-10H,1-2H2,(H2,11,12,13)(H2,14,15,16)/t3-,5-,6-/m1/s1 | [InChIKey]
XPYBSIWDXQFNMH-UYFOZJQFSA-N | [SMILES]
C(OP(O)(O)=O)C([C@H]([C@@H]([C@@H](COP(O)(O)=O)O)O)O)=O | [EPA Substance Registry System]
D-Fructose, 1,6-bis(dihydrogen phosphate) (488-69-7) |
| Hazard Information | Back Directory | [Description]
D-fructose 1,6-bis(dihydrogen phosphate) is a cytoprotective natural sugar phosphate for the potential treatment of cardiovascular ischemia, sickle cell anemia and asthma. | [Chemical Properties]
D-fructose 1,6-bis(dihydrogen phosphate) is a white or off-white crystalline powder that is soluble in water and virtually insoluble in ethanol, acetone and ether. In life activities, it participates in the synthesis and catabolism of ATP (adenosine triphosphate) as a carrier of high-energy phosphate bonds.
| [Uses]
Cardioprotectant for ischemic disorders. | [Application]
D-fructose 1,6-bis(dihydrogen phosphate) is an important metabolic intermediate and an energy carrier. It is primarily used in pharmaceuticals to provide a source of energy to cells and improve the metabolic rate of patients and also used in the food industry as a food additive due to its ability to enhance the aroma and taste of food products.
| [Definition]
ChEBI: D-fructofuranose 1,6-bisphosphate is the furanose form of D-fructose 1,6-bisphosphate. It is functionally related to a D-fructofuranose. It is a conjugate acid of a D-fructofuranose 1,6-bisphosphate(4-). | [Mechanism of action]
D-fructose 1,6-bis(dihydrogen phosphate) acts by stimulating anaerobic glycolysis which generates adenosine triphosphate under ischemic conditions. |
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