ChemicalBook--->CAS DataBase List--->488841-24-3

488841-24-3

488841-24-3 Structure

488841-24-3 Structure
IdentificationBack Directory
[Name]

4-OH-E1-1-N3Ade
[CAS]

488841-24-3
[Synonyms]

4-OH-E1-1-N3Ade
Reaxys ID: 9304590
Estrone Impurity 16
4-Hydroxy Estrone 1-N3-Adenine
1-(6-AMino-3H-purin-3-yl)-3,4-dihydroxyestra-1,3,5(10)-trien-17-one
Estra-1,3,5(10)-trien-17-one, 1-(6-amino-3H-purin-3-yl)-3,4-dihydroxy-
[Molecular Formula]

C23H25N5O3
[MDL Number]

MFCD30719957
[MOL File]

488841-24-3.mol
[Molecular Weight]

419.48
Chemical PropertiesBack Directory
[Melting point ]

>230°C (dec.)
[storage temp. ]

Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ]

DMSO (Slightly), Methanol (Slightly)
[form ]

Solid
[color ]

Beige to Dark Beige
Hazard InformationBack Directory
[Uses]

4-Hydroxy Estrone 1-N3-Adenine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. The N3Ade depurinating adducts could serve as biomarkers to predict the risk of breast cancer.
[Uses]

4-Hydroxy Estrone 1-N3-Adenine is an estrogen metabolite formed with DNA which can lead to the mutations that initiate breast, prostate, and other types of cancer. The N3Ade depurinating adducts could serve as biomarkers to predict the risk of breast cancer.
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