| Identification | Back Directory | [Name]
AC-ASP(GLU-OH)-OH | [CAS]
4910-46-7 | [Synonyms]
Spaglumic
Ac-D(E)-OH
Ac-β-Asp-Glu-OH
AC-ASP(GLU-OH)-OH
AC-BETA-ASP-GLU-OH
n-acetyl-b-asp-glu
Ac-L-βAsp-L-Glu-OH
N-ACETYL-BETA-ASP-GLU
N-Acetyl-βAsp-L-Glu-OH
AC-ASP(GLU-OH)-OH USP/EP/BP
N-Acetyl-β-Asp-Glu (β-NAAG)
N-acetylaspartylglutamate (NAAG)
L-Glutamic acid,N-acetyl-L-b-aspartyl-
L-Glutamic acid, N-acetyl-L-β-aspartyl-
Ac-b-Asp-Glu-OH, b-NAAG, b-SpagluMic acid
N-(N-Acetyl-L-β-aspartyl)-L-glutamic acid
N-ACETYL-L-ASPARTYL-L-GLUTAMIC ACID NAAG , SPAGLUMIC ACID | [Molecular Formula]
C11H16N2O8 | [MDL Number]
MFCD00133559 | [MOL File]
4910-46-7.mol | [Molecular Weight]
304.25 |
| Chemical Properties | Back Directory | [Melting point ]
113-115 °C (decomp) | [Boiling point ]
775.8±60.0 °C(Predicted) | [density ]
1.472±0.06 g/cm3(Predicted) | [storage temp. ]
−20°C
| [form ]
powder | [pka]
3.28±0.10(Predicted) | [color ]
white to faint yellow | [InChI]
1S/C11H16N2O8/c1-5(14)12-7(11(20)21)4-8(15)13-6(10(18)19)2-3-9(16)17/h6-7H,2-4H2,1H3,(H,12,14)(H,13,15)(H,16,17)(H,18,19)(H,20,21) | [InChIKey]
GUCKKCMJTSNWCU-BQBZGAKWSA-N | [SMILES]
CC(=O)NC(CC(=O)NC(CCC(O)=O)C(O)=O)C(O)=O |
| Hazard Information | Back Directory | [Uses]
neurotransmitter; mGluR3 receptors | [Definition]
ChEBI: Spaglumic acid is a peptide. | [Biological Activity]
The most abundant peptide neurotransmitter in the mammalian CNS. A weak activator of NMDA receptors, and a highly selective agonist for mGlu 3 receptors. Neuroprotective under non-hydrolysing conditions in vivo . |
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