| Identification | Back Directory | [Name]
PACHYCARPINE | [CAS]
492-08-0 | [Synonyms]
D-spartine
d-Sparteine
PACHYCARPINE
Sparteine d-isomer
PACHYCARPINE USP/EP/BP
(+)-Sparteine, 98%, from Parochetus communis D. Don
(1R,2S,9R,10R)-7,15-Diazatetracyclo[7.7.1.02,7.010,15]heptadecane
(7R,7aR,14R,14aS)-Dodecahydro-2H,6H-7,14-methanodipyrido[1,2-a:1',2'-e][1,5]diazocine
(7R,7aR,14R,14aS)-Dodecahydro-7,14-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine
7,14-Methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine, dodecahydro-, (7R,7aR,14R,14aS)-
(7R)-1,3,4,7,7aβ,8,9,10,11,13,14,14aα-Dodecahydro-7β,14β-methano-2H,6H-dipyrido[1,2-a:1',2'-e][1,5]diazocine | [EINECS(EC#)]
805-899-0 | [Molecular Formula]
C15H26N2 | [MDL Number]
MFCD00869353 | [MOL File]
492-08-0.mol | [Molecular Weight]
234.38 |
| Chemical Properties | Back Directory | [Melting point ]
201℃ | [Boiling point ]
174°C/8mmHg(lit.) | [density ]
1.08 | [refractive index ]
n/D1.527 | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
Chloroform (slightly), Ethanol | [form ]
liquid | [pka]
10.08±0.20(Predicted) | [color ]
Colourless to Light Yellow | [λmax]
202nm(CH3CN)(lit.) | [InChI]
InChI=1S/C15H26N2/c1-3-7-16-11-13-9-12(14(16)5-1)10-17-8-4-2-6-15(13)17/h12-15H,1-11H2/t12-,13-,14-,15+/m1/s1 | [InChIKey]
SLRCCWJSBJZJBV-TUVASFSCSA-N | [SMILES]
N12CCCC[C@@]1([H])[C@]1([H])C[C@]([H])(C2)[C@@]2([H])CCCCN2C1 | [CAS DataBase Reference]
492-08-0 |
| Hazard Information | Back Directory | [Uses]
(+)-Sparteine is a natural alkaloid acting as a ganglionic blocking agent. (+)-Sparteine competitively blocks nicotinic ACh receptor in the neurons. | [Safety Profile]
Poison by subcutaneous and intravenous routes. When heated to decomposition it emits toxic fumes of NOx. | [storage]
Store at -20°C, protect from light | [References]
[1] Voitenko S, et al. Effect of (+)-sparteine on nicotinic acetylcholine receptors in the neurons of rat superior cervical ganglion. Mol Pharmacol. 1991 Aug;40(2):180-5. PMID:1715014 |
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