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493-48-1

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493-48-1 Structure

493-48-1 Structure
IdentificationBack Directory
[Name]

SALSOLIDINE
[CAS]

493-48-1
[Synonyms]

salsolidin
SALSOLIDINE
Salsolindine
(R)-Salsolidine
(s)-salsolidine
(R)-(+)-Salsolidine
(S)-4-bromo-3-(pent-4-en-2-yloxy)benzonitrile
6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro-isoquinolin
1,2,3,4-tetrahydro-6,7-dimethoxy-1-methyl-isoquinolin
2,3,4-tetrahydro-6,7-dimethoxy-1-methyl-(s)-isoquinolin
(S)-1,2,3,4-Tetrahydro-6,7-dimethoxy-1-methylisoquinoline
(R)-1-Methyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
(1S)-1,2,3,4-Tetrahydro-1-methyl-6,7-dimethoxyisoquinoline
(1S)-6,7-Dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline
rac-1α*-Methyl-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline
Isoquinoline, 1,2,3,4-tetrahydro-6,7-dimethoxy-1-methyl-, (1S)-
[Molecular Formula]

C12H17NO2
[MDL Number]

MFCD01717224
[MOL File]

493-48-1.mol
[Molecular Weight]

207.27
Chemical PropertiesBack Directory
[Melting point ]

47.5-48.5 °C
[Boiling point ]

72 °C
[density ]

1.034±0.06 g/cm3(Predicted)
[pka]

9.08±0.40(Predicted)
Hazard InformationBack Directory
[Uses]

(S)-Salsolidine is a weak monoamine oxidase (MAO) inhibitor (Ki=63 μM). The R enantiomer of Salsolidine is more potent than the S form (Ki=26 μM)[1].
[References]

[1] Dostert P, et al. Dopamine-derived alkaloids in alcoholism and in Parkinson's and Huntington's diseases. J Neural Transm. 1988;74(2):61-74. DOI:10.1007/BF01245140
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