| Identification | Back Directory | [Name]
NORNICOTINE, DL-(RG) | [CAS]
494-97-3 | [Synonyms]
Nornicotin
(s)-nicotin
dl-Norcitine
l-Nor-nicotine
S-(-)-Nornicotine
-3-(Pyrrolidin-2-yl)
NORNICOTINE, DL-(RG)
Nicotine EP Impurity F
(S)-2-(3-Pyridyl)pyrrolidine
Nicotine, 1'-demethyl-, (S)-
3-(2S)-2-Pyrrolidinylpyridine
(S)-3-Pyrrolidin-2-yl-pyridine
3-[(S)-2-Pyrrolidinyl]pyridine
3-((2S)PYRROLIDIN-2-YL)PYRIDINE
Pyridine, 3-(2S)-2-pyrrolidinyl-
3-[(2S)-Pyrrolidine-2α-yl]pyridine
Pyridine, 3-(2-pyrrolidinyl)-, (S)-
Nicotine EP Impurity F (nornicotine ) | [Molecular Formula]
C9H12N2 | [MDL Number]
MFCD00016913 | [MOL File]
494-97-3.mol | [Molecular Weight]
148.21 |
| Chemical Properties | Back Directory | [alpha ]
D22 -89° (c = 100) | [Boiling point ]
bp 270°; bp11 131°; bp3 105-107° | [density ]
d420 1.0737 | [refractive index ]
nD20 1.5378 | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [solubility ]
Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Sparingly) | [form ]
Oil | [pka]
9.09±0.10(Predicted) | [color ]
visc liquid | [Odor]
slt amine odor | [Henry's Law Constant]
7.2×103 mol/(m3Pa) at 25℃, HSDB (2015) | [Stability:]
Light Sensitive | [EPA Substance Registry System]
Pyridine, 3-(2S)-2-pyrrolidinyl- (494-97-3) |
| Hazard Information | Back Directory | [Chemical Properties]
Pale Yellow to Reddish Brown Oil | [Uses]
(S)-Nornicotine is a metabolite of Nicotine (N412420). Can catalyze aqueous aldol reactions. | [Uses]
Agricultural or horticultural insecticide. | [Definition]
ChEBI: A pyridine alkaloid that is nicotine lacking the methyl group on the pyrrolidine nitrogen. | [Production Methods]
Commercial production of nornicotine, particularly the high-purity (S)-enantiomer, has evolved from traditional tobacco extraction to sophisticated synthetic and chemoenzymatic methods. One advanced approach begins with myosmine, a compound derived from nicotinic acid, which is then converted into (S)-nornicotine using highly selective biocatalysts such as imine reductases. Enzyme-driven processes that enable efficient, scalable production while minimizing impurities like tobacco-specific nitrosamines have been developed. Another method involves converting racemic (R,S)-nornicotine into high-purity (S)-nornicotine through a combination of immobilized enzymes and reducing agents | [Mechanism of action]
Broad-spectrum and fast acting. Mainly respiratory action but some contact and stomach activity | [Safety Profile]
Poison by intraperitoneal andintravenous routes. About 1/3 the toxicity of nicotine.Causes faintness, prostration, muscular weakness, severenausea, vomiting, diarrhea, and collapse withoutconvulsions. An insecticide. When heated todecomposition it em | [IC 50]
Human Endogenous Metabolite | [Pesticide Type]
Insecticide; Metabolite |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
BioPharmaMatrix,Inc.
|
| Telephone: |
0510-86010668 13395169561; |
| Website: |
http://www.biopharmamatrix.com |
| Company Name: |
Wuxi AppTec
|
| Telephone: |
022-59987777 13552403979 |
| Website: |
www.labnetwork.com |
|