| Identification | Back Directory | [Name]
2,5-DICHLOROPHENYLTHIOUREA | [CAS]
4949-85-3 | [Synonyms]
LABOTEST-BB LT00454457
2,5-DICHLOROPHENYLTHIOUREA
(2,5-dichlorophenyl)-thioure
1-(2,5-Dichlorophenyl)thiourea
1-(2,5-dichlorophenyl)-2-thio-ure
1-(2,5-DICHLOROPHENYL)-2-THIOUREA
Thiourea, N-(2,5-dichlorophenyl)- | [EINECS(EC#)]
674-277-7 | [Molecular Formula]
C7H6Cl2N2S | [MDL Number]
MFCD00041154 | [MOL File]
4949-85-3.mol | [Molecular Weight]
221.11 |
| Questions And Answer | Back Directory | [Synthesis]
Take 0.1 mol of 2,5-dichloroaniline, add 9 ml of HCl and 25 ml of water, and heat the solution in a round-bottom flask at about 60-70°C for about 1 hour. Cool the mixture for about 1 hour, and then slowly add 0.1 mol of ammonium thiocyanate to the solution. Now reflux the solution for about 4 hours. Add 20 ml of water to the solution while stirring constantly. Filter the solution and dry to obtain powdered 2,5-dichlorophenylthiourea. | [Uses]
2,5-Dichlorophenylthiourea is a pharmaceutical intermediate that can be prepared in one step from 2,5-dichloroaniline. Literature reports that 2,5-dichlorophenylthiourea can be used to prepare the bactericidal compound N-(2,5-dichlorophenyl)-4-(pyridin-2-yl)-5-(1H-1,2,4-triazol-1-yl)thiazol-2-amine. | [Application]
Zhang Mu et al. reported that 2,5-dichlorophenylthiourea can be used to prepare the following 2-aminothiazole derivative compound, 6hN-(2,5-dichlorophenyl)-4-(pyridin-2-yl)-5-(1H-1,2,4-triazol-1-yl)thiazole-2-amine. 2-Aminothiazole derivatives not only possess excellent insecticidal, fungicidal, herbicidal, and plant growth-regulating activities, but also exhibit outstanding pharmacological activities. Due to their simple synthetic methods and diverse biological activities, they have attracted considerable attention from pesticide and pharmaceutical researchers. |
| Chemical Properties | Back Directory | [Melting point ]
193-194°C | [Boiling point ]
317.4±52.0 °C(Predicted) | [density ]
1.563±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [pka]
11.83±0.70(Predicted) | [BRN ]
2212146 |
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J & K SCIENTIFIC LTD.
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https://www.jkchemical.com |
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Alfa Aesar
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Energy Chemical
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