| Identification | Back Directory | [Name]
G418 | [CAS]
49863-47-0 | [Synonyms]
G418
Aids114952
Aids-114952
GENETICIN(R)
ANTIBIOTIC G418
G 418 DISULFATE
Gentamicin G-418
Gentiomycin G-418
GENETICIN DISULFATE
GENETICIN(R) DISULFATE
G418 SULFATE ANTIBIOTIC
GENETICIN DISULFATE SALT
ANTIBIOTIC G418 DISULFATE
AMINOGLYCOSIDE ANTIBIOTIC
GENETICIN(R) DISULFATE SALT
ANTIBIOTIC G418 DISULFATE SALT
4-O-(2-Amino-2,7-dideoxy-α-D-glycero-D-gluco-heptopyranosyl)-6-O-[4-C-methyl-3-(methylamino)-3-deoxy-β-L-arabinopyranosyl]-2-deoxy-D-streptamine
D-Streptamine, O-2-amino-2,7-dideoxy-D-glycero-α-D-gluco-heptopyranosyl-(1→4)-O-[3-deoxy-4-C-methyl-3-(methylamino)-β-L-arabinopyranosyl-(1→6)]-2-deoxy-
O-2-AMINO-2,7-DIDEOXY-DELTA-GLY-CERO-ALPHA-D-GLUCO-HEPTO-PYRANOSYL[1->4]-O-3-DEOXY-4C-METHYL-3-[METHYL-AMINO]-BETA-L-ARABINOPYRONOSYL-DELTA-STREPTAMINE, DISULFATE SALT
(2R,3S,4R,5R,6S)-5-Amino-6-(((1R,2S,3S,4R,6S)-4,6-diamino-3-(((2R,3R,4R,5R)-3,5-dihydroxy-5-methyl-4-(methylamino)tetrahydro-2H-pyran-2-yl)oxy)-2-hydroxycyclohexyl)oxy)-2-((R)-1-hydroxyethyl)tetrahydro-2H-pyran-3,4-diol | [Molecular Formula]
C20H40N4O10 | [MDL Number]
MFCD30541267 | [MOL File]
49863-47-0.mol | [Molecular Weight]
496.55 |
| Chemical Properties | Back Directory | [Melting point ]
>193°C (dec.) | [Boiling point ]
760.3±60.0 °C(Predicted) | [density ]
1.47±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
H2O: 50 mg/mL | [form ]
white powder | [pka]
13.29±0.70(Predicted) | [color ]
White to Off-White | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Uses]
Geneticin Disulfate Salt, is an aminoglycoside antibiotic, structurlly similar to Gentamicin B1. It is produced by Micromonospora rhodorangea. G418 blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells. | [Definition]
ChEBI: An aminoglycoside antibiotic produced by Micromonospora rhodorangea. It blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells. |
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