| Identification | Back Directory | [Name]
Corydamine | [CAS]
49870-84-0 | [Synonyms]
Corydamin
Corydamine
6-(1,3-Dioxolo[4,5-h]isoquinolin-7-yl)-N-methyl-1,3-benzodioxole-5-ethanamine
1,3-Benzodioxole-5-ethanamine, 6-(1,3-dioxolo[4,5-h]isoquinolin-7-yl)-N-methyl-
6-(1,3-Dioxolo[4,5-h]isoquinolin-7-yl)-N-methyl-1,3-benzodioxole-5-ethan-1-amine | [Molecular Formula]
C20H18N2O4 | [MOL File]
49870-84-0.mol | [Molecular Weight]
350.37 |
| Chemical Properties | Back Directory | [Boiling point ]
545.0±50.0 °C(Predicted) | [density ]
1.334±0.06 g/cm3(Predicted) | [solubility ]
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. | [form ]
Cryst. | [pka]
10.24±0.10(Predicted) |
| Hazard Information | Back Directory | [Uses]
Corydamine, 3-arylisoquinoline alkaloid, is a potent DNA topoisomerase I/II inhibitor. Corydamine has anti-cancer activity[1]. | [IC 50]
Topoisomerase I; Topoisomerase II | [References]
[1] Xuemei Deng, et al. Design, synthesis and anti-hepatocellular carcinoma activity of 3-arylisoquinoline alkaloids. Eur J Med Chem. 2022 Jan 15;228:113985. DOI:10.1016/j.ejmech.2021.113985 |
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cjbscvictory
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13348960310 |
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Biorbyt Ltd.
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