4999-79-5

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4999-79-5 Structure

Identification	Back Directory
[Name] 17β-Estradiol 3-O-Sulfate SodiuM Salt
[CAS] 4999-79-5
[Synonyms] 17β-Estradiol sodium sulfate 17β-Estradiol sulfate sodium 17β-Estradiol 3-sulfate sodium SODIUM 17B-ESTRADIOL 3-SULFATE 17B-estradiol 3-sulfate sodium b-Estradiol 3-sulfate sodium salt oestradiol 3-sulfate, sodium salt 17BETA-ESTRADIOL 3-SULFATE SODIUM 17-Beta-Estradiol-3-O-Sulfate SodiuM 17β-Estradiol 3-Sulphate Sodium Salt β-Estradiol 3-sulfate sodium salt 17β-Estradiol 3-Sulphate, Sodium Salt 17β-Estradiol 3-O-Sulfate Sodium Salt 17β-Estradiol 3-O-Sulfate Sodium Salt 17BETA-ESTRADIOL 3-SULFATE SODIUM SALT 17-BETA-ESTRADIOL 3-SULPHATE, SODIUM SALT 1,3,5(10)-Estratriene-3,17β-diol 3-sulfate 3,17β-Dihydroxy-1,3,5(10)-estratriene 3-sulfate 1,3,5(10)-ESTRATRIEN-3,17BETA-DIOL 3-SULFATE SODIUM 1,3,5[10]-ESTRATRIENE-3,17BETA-DIOL 3-SULFATE SODIUM SALT 1, 3, 5(10)-ESTRATRIEN-3, 17β-DIOL 3-SULPHATE, SODIUM SALT 1,3,5(10)-ESTRATRIEN-3,17-BETA-DIOL 3-SULPHATE, SODIUM SALT 17β-Estradiol 3-sulfate sodium\|\|\|17β-Estradiol sulfate sodium 3,17BETA-DIHYDROXY-1,3,5[10]-ESTRATRIENE 3-SULFATE SODIUM SALT Estra-1,3,5(10)-triene-3,17-diol(17b)-, 3-(hydrogen sulfate), sodiumsalt (1:1) 1,3,5(10)-Estratriene-3,17β-diol 3-sulfate, 3,17β-Dihydroxy-1,3,5(10)-estratriene 3-sulfate
[Molecular Formula] C18H23NaO5S
[MDL Number] MFCD00056553
[MOL File] 4999-79-5.mol
[Molecular Weight] 374.43

Chemical Properties	Back Directory
[Melting point ] 207 °C
[storage temp. ] Hygroscopic, -20°C Freezer, Under inert atmosphere
[solubility ] DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly), Water (Slightly)
[form ] Solid
[color ] White to Off-White
[Stability:] Hygroscopic

Hazard Information	Back Directory
[Uses] 17β-Estradiol 3-O-Sulfate Sodium Salt is a neuroactive steroid used in the studies of human recombinant p1 γ-aminobutyric acid type C (GABAC) recptors.
[Uses] β-Estradiol 3-sulfate sodium salt has been used to measure the estradiol level from culture supernatant in ultra-performance liquid chromatography-tandem mass spectrometry.
[General Description] β-Estradiol is secreted by developing ovaries and is predominant during premenopause in women.
[Biochem/physiol Actions] β-Estradiol is a steroid hormone involved in a number of organ functions. It is significantly associated with brain functions including neuroprotection, neurogenesis and synaptic plasticity. β-Estradiol maintains bone homeostasis, hence it is preferred for osteoporosis therapy. 17-β-Estradiol is the most active estrogen generated in our body. During postmenopausal, 17-β-estradiol inhibits oxidative modification in low density lipoprotein. This indicates that estrogen replacement therapy might be useful in treating cardiovascular disease.

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