| Identification | Back Directory | [Name]
2-(hydroxymethyl)-2-[[2-hydroxy-3-(5-methyl-2,3-diphenylindol-1-yl)propyl]amino]propane-1,3-diol | [CAS]
500015-22-5 | [Synonyms]
PknB-IN-2
2-(hydroxymethyl)-2-[[2-hydroxy-3-(5-methyl-2,3-diphenylindol-1-yl)propyl]amino]propane-1,3-diol
1,3-Propanediol, 2-(hydroxymethyl)-2-[[2-hydroxy-3-(5-methyl-2,3-diphenyl-1H-indol-1-yl)propyl]amino]- | [Molecular Formula]
C28H32N2O4 | [MDL Number]
MFCD03084676 | [MOL File]
500015-22-5.mol | [Molecular Weight]
460.56 |
| Hazard Information | Back Directory | [Uses]
PknB-IN-2 (Compound 10) is a Mycobacterium tuberculosis protein kinase B (PknB) inhibitor with an IC50 of 12.1 μM[1]. | [References]
[1] Thongdee P, et al. Virtual Screening Identifies Novel and Potent Inhibitors of Mycobacterium tuberculosis PknB with Antibacterial Activity. J Chem Inf Model. 2022 Aug 22. DOI:10.1021/acs.jcim.2c00531 |
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