| Identification | Back Directory | [Name]
Feruloylputrescine | [CAS]
501-13-3 | [Synonyms]
NSC 602818
Subaphyllin
Subaphylline
Feruloylputrescine
N-Feruloylputrescine
N-(4-Aminobutyl)-3-(4-hydroxy-3-methoxyphenyl)acrylamide
N-(4-Aminobutyl)-3-(4-hydroxy-3-methoxyphenyl)propenamide
N-(4-Aminobutyl)-3-(4-hydroxy-3-methoxyphenyl)-2-propenamide
2-Propenamide, N-(4-aminobutyl)-3-(4-hydroxy-3-methoxyphenyl)-
(E)-N-(4-aminobutyl)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enamide | [Molecular Formula]
C14H20N2O3 | [MDL Number]
MFCD01736565 | [MOL File]
501-13-3.mol | [Molecular Weight]
264.32 |
| Chemical Properties | Back Directory | [Boiling point ]
512℃ | [density ]
1.156 | [Fp ]
263℃ | [solubility ]
Water | [form ]
Solid | [pka]
9.78±0.35(Predicted) | [color ]
Yellowish | [LogP]
0.620 (est) |
| Hazard Information | Back Directory | [Description]
Salsola subaphylla contains this alkaloid which is extremely hygroscopic and for
which no definite melting point has been obtained. It gives crystalline salts and
derivatives, e.g. the hydrochloride, melting over a very wide range of temperature;
the hydriodide which behaves similarly to the hydrochloride, picrate, m.p.
218.5°C. On hydrogenation over Pt02 it yields the dihydro derivative giving a
hydrochloride, m.p. 139-140oC and a picrate, m.p. 174.6-175°C. When boiled
with 30 per cent KOH it forms putrescine and ferulic acid and has the probable
structure given above. | [Uses]
Feruloylputrescine is an effector of plant root systems, influencing development of nutrient gathering root systems. Inhibition of the formation of this compound causes the development of a dominant or ‘tap’ root. | [Definition]
ChEBI: Subaphyllin is a hydroxycinnamic acid. | [in vivo]
Feruloylputrescine (administered via diet, 10 mg per g of diet daily for 6 weeks) significantly reduces TMA and TMAO levels in high-fat diet-induced mice[1]. | Animal Model: | High-fat diet-induced C57BL/6 mouse model[1] | | Dosage: | 10 mg/g diet | | Administration: | Administered via diet, 10 mg/g diet daily for 6 weeks | | Result: | Significantly reduced TMA and TMAO levels. |
| [References]
Ryabinin, Il'na., Dokl. Akad. Nauk SSSR, 67, 513 (1949) |
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Rhawn Reagent Gold
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