| Identification | Back Directory | [Name]
MN-25 | [CAS]
501927-29-3 | [Synonyms]
MN-25
MN25 high purity
MN-25-2-methyl derivative
1H-Indole-3-carboxaMide, 7-Methoxy-2-Methyl-1-[2-(4-Morpholinyl)ethyl]-N-[(
7-methoxy-2-methyl-1-(2-morpholin-4-ylethyl)-N-[(1R,3S,4S)-2,2,4-trimethyl-3-bicyclo[2.2.1]heptanyl]indole-3-carboxamide
1H-Indole-3-carboxaMide, 7-Methoxy-2-Methyl-1-[2-(4-Morpholinyl)ethyl]-N-[(1S,2S,4R)-1,3,3-triM ethylbicyclo[2.2.1]hept-2-yl]- | [Molecular Formula]
C27H39N3O3 | [MOL File]
501927-29-3.mol | [Molecular Weight]
453.62 |
| Chemical Properties | Back Directory | [Boiling point ]
618.9±55.0 °C(Predicted) | [density ]
1.23±0.1 g/cm3(Predicted) | [solubility ]
DMF: 30 mg/ml; DMF:PBS (pH 7.2) (1:5): 0.16 mg/ml; DMSO: 20 mg/ml; Ethanol: 10 mg/ml | [form ]
A crystalline solid | [pka]
14.43±0.60(Predicted) |
| Hazard Information | Back Directory | [Description]
MN-25-2-methyl derivative is a cannabinoid (CB) receptor ligand with Ki values of 8 and 29 nM at the central CB1 receptor and peripheral CB2 receptor, respectively. This product is intended for forensic and research applications. | [Uses]
MN-25, is a synthetic cannabinoid (CB) with greater affinity for the peripheral CB2 receptor (Ki = 11 nM) than for the central CB1 receptor (Ki = 245 nM). Synthetic Cannabinoids | [References]
[1] STEPHEN T. WROBLESKI. Rational Design and Synthesis of an Orally Active Indolopyridone as a Novel Conformationally Constrained Cannabinoid Ligand Possessing Antiinflammatory Properties[J]. Journal of Medicinal Chemistry, 2003, 46 11: 2110-2116. DOI: 10.1021/jm020329q |
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