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50423-15-9

50423-15-9 Structure

50423-15-9 Structure
IdentificationBack Directory
[Name]

Methylcardol triene
[CAS]

50423-15-9
[Synonyms]

Methylcardol triene
1,3-Benzenediol, 2-methyl-5-(8Z,11Z)-8,11,14-pentadecatrienyl- (9CI)
[Molecular Formula]

C22H32O2
[MOL File]

50423-15-9.mol
[Molecular Weight]

328.49
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMF: 20 mg/ml; DMSO: 15 mg/ml; Ethanol: 22 mg/ml; Ethanol:PBS(pH 7.2) (1:1): 0.5 mg/ml
[form ]

A neat oil
Hazard InformationBack Directory
[Description]

Methylcardol triene is a phenol found in cashew nut shell liquid that inhibits α-glucosidase (IC50 = 39.6 μM).1 It is schistosomicidal, killing 100% of adult S. mansoni worms after 24 hours when used at concentrations of 100 and 200 μM.2 It has been used as a starting material for the synthesis of mono- and bis-benzoxazines.3
[Uses]

2-Methylcardol triene is a phenol found in cashew nut shell liquid that inhibits α-glucosidase (IC50=39.6 μM). 2-Methylcardol triene is schistosomicidal, killing 100% of adult S. mansoni worms after 24 hours when used at concentrations of 100 and 200 μM. 2-Methylcardol triene has been used as a starting material for the synthesis of mono- and bis-benzoxazines.
[References]

1. Toyomizu, M., Sugiyama, S., Jin, R.L., et al. α-Glucosidase and aldoser reductase inhibitors: Constituents of cashew, anacardium occidentale, nut shell liquids Phytother. Res. 7,252-254(1993).
2. Attanasi, O.A., Behalo, M.S., Favi, G., et al. Solvent free synthesis of novel mono- and bis-benzoxazines from cashew nut shell liquid components Curr. Org. Chem. 16(21),2613-2621(2012).
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