| Identification | Back Directory | [Name]
ALPHA-ELEOSTEARIC ACID | [CAS]
506-23-0 | [Synonyms]
C08315
a-EleostearicAcid
α-Eleostearic Acid
ALPHA-ELEOSTEARIC ACID
9(Z),11(E),13(E)-OCTADECATRIENOIC ACID
(9E,11Z,13E)-9,11,13-Octadecatriensure
(E,Z,E)-octadeca-9,11,13-trienoic acid
9(E),11(Z),13(E)-Octadecatrienoic acid
(9Z,11E,13E)-9,11,13-Octadecatrienoic acid
(9E,11Z,13E)-9,11,13-octadecatrienoic acid
(9Z,11E,13E)-octadeca-9,11,13-trienoic acid
9,11,13-Octadecatrienoic acid, (9Z,11E,13E)- | [EINECS(EC#)]
208-029-2 | [Molecular Formula]
C18H30O2 | [MDL Number]
MFCD05864023 | [MOL File]
506-23-0.mol | [Molecular Weight]
278.43 |
| Chemical Properties | Back Directory | [Melting point ]
49°C | [Boiling point ]
361.24°C (rough estimate) | [density ]
0.9028 | [refractive index ]
1.5112 | [storage temp. ]
Amber Vial, -20°C Freezer, Under inert atmosphere | [solubility ]
Aqueous Base (Slightly), Chloroform (Slightly), Methanol (Very Slightly) | [form ]
Solid | [pka]
4.78±0.10(Predicted) | [color ]
White to Off-White | [Stability:]
Light Sensitive | [InChI]
InChI=1S/C18H30O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h5-10H,2-4,11-17H2,1H3,(H,19,20)/b6-5+,8-7+,10-9- | [InChIKey]
CUXYLFPMQMFGPL-WPOADVJFSA-N | [SMILES]
C(O)(=O)CCCCCCC/C=C\C=C\C=C\CCCC |
| Hazard Information | Back Directory | [Uses]
α-Eleostearic Acid, is a conjugated polyunsaturated fatty acid commonly found in plant seed oil. It has shown potential as a tumor growth suppressor. In colon cancer Caco-2 cells, α-ESA induced apoptosis through up-regulation of GADD45, p53, and PPARγ. | [Definition]
ChEBI: (9Z,11E,13E)-octadeca-9,11,13-trienoic acid is a conjugated linolenic acid having three fully-conjugated double bonds at positions 9, 11 and 13, in cis, trans and trans configurations, respectively. | [in vivo]
α-Eleostearic acid (0.5% of total lipid given; p.o.) inhibits Sodium Arsenite-induced oxidative stress, including reversal of antioxidant enzyme activity and reduction of lipid peroxidation levels[2].
Oral administration of tung oil, naturally rich inα-Eleostearic acid, to mice limits tumor growth and metastasis in an aggressive TNBC orthotopic xenograft model[3]. |
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Alfa Chemistry
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BOC Sciences
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