| Identification | Back Directory | [Name]
3β,5,14,19-Tetrahydroxy-5β-bufa-20,22-dienolide | [CAS]
508-79-2 | [Synonyms]
Hellebrigenol
3β,5,14,19-Tetrahydroxy-5β-bufa-20,22-dienolide
Hellebrigenol(19-Hydroxytelocinobufagin,Gellebrigeno)
Bufa-20,22-dienolide, 3,5,14,19-tetrahydroxy-, (3β,5β)- | [Molecular Formula]
C24H34O6 | [MOL File]
508-79-2.mol | [Molecular Weight]
418.53 |
| Chemical Properties | Back Directory | [Melting point ]
146-153 °C | [Boiling point ]
635.4±55.0 °C(Predicted) | [density ]
1.370±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
14.33±0.70(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Hellebrigenol is a metabolite of bufadienolides with antitumor activity[1]. | [References]
[1] Lingyu Han, et al. Metabolites profiling of 10 bufadienolides in human liver microsomes and their cytotoxicity variation in HepG2 cell. Anal Bioanal Chem. 2016 Apr;408(10):2485-95. DOI:10.1007/s00216-016-9345-y |
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