| Identification | Back Directory | [Name]
L-Lysine, L-lysyl-L-arginyl-L-prolyl-L-prolyl-L-lysyl-L-leucylglycyl-L-glutaminyl-L-isoleucylglycyl-L-arginyl-L-alanyl-L-lysyl-L-arginyl-L-valyl-L-valyl-L-isoleucyl-L-α-glutamyl-L-α-aspartyl-L-α-aspartyl-L-arginyl-L-isoleucyl-L-α-aspartyl-L-α-aspartyl-L-valyl-L-leucyl- | [CAS]
508181-45-1 | [Synonyms]
CaMKII inhibitory peptide KIIN
L-Lysine, L-lysyl-L-arginyl-L-prolyl-L-prolyl-L-lysyl-L-leucylglycyl-L-glutaminyl-L-isoleucylglycyl-L-arginyl-L-alanyl-L-lysyl-L-arginyl-L-valyl-L-valyl-L-isoleucyl-L-α-glutamyl-L-α-aspartyl-L-α-aspartyl-L-arginyl-L-isoleucyl-L-α-aspartyl-L-α-aspartyl-L-valyl-L-leucyl- | [Molecular Formula]
C136H240N44O39 | [MOL File]
508181-45-1.mol | [Molecular Weight]
3115.63 |
| Chemical Properties | Back Directory | [density ]
1.46±0.1 g/cm3(Predicted) | [Sequence]
Lys-Arg-Pro-Pro-Lys-Leu-Gly-Gln-Ile-Gly-Arg-Ala-Lys-Arg-Val-Val-Ile-Glu-Asp-Asp-Arg-Ile-Asp-Asp-Val-Leu-Lys |
| Hazard Information | Back Directory | [Uses]
CaMKII inhibitory peptide KIIN is a potent inhibitor of CaMKII[1][2]. | [References]
[1] Shlomit Boguslavsky, et al. Myo1c binding to submembrane actin mediates insulin-induced tethering of GLUT4 vesicles. Mol Biol Cell. 2012 Oct;23(20):4065-78. DOI:10.1091/mbc.E12-04-0263
[2] B H Chang, et al. Calcium/calmodulin-dependent protein kinase II inhibitor protein: localization of isoforms in rat brain. Neuroscience. 2001;102(4):767-77. DOI:10.1016/s0306-4522(00)00520-0 |
|
|