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5088-90-4

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5088-90-4 Structure

5088-90-4 Structure
IdentificationBack Directory
[Name]

Liensinine diperchlorate
[CAS]

5088-90-4
[Synonyms]

Liensinine diperchlorate
Liensinine diperchlorate, 98%, from Nelumbo nucifera Gaertn.
[Molecular Formula]

C37H43ClN2O10
[MDL Number]

MFCD16879086
[MOL File]

5088-90-4.mol
[Molecular Weight]

711.21
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 100 mg/mL (123.20 mM; Need ultrasonic)
[form ]

powder
[color ]

White
Safety DataBack Directory
[HS Code ]

29389090
Hazard InformationBack Directory
[Uses]

Liensinine Diperchlor?ate is a major isoquinoline alkaloid, extracted from the seed embryo of Nelumbo nucifera Gaertn. Liensinine Diperchlor?ate inhibits late-stage autophagy/mitophagy through blocking autophagosome-lysosome fusion. Liensinine Diperchlor?ate has a wide range of biological activities, including anti-arrhythmias, anti-hypertension, anti-pulmonary fibrosis, relaxation on vascular smooth muscle, etc[1].
[storage]

Store at -20°C
[References]

[1] Zhou J, et al. A novel autophagy/mitophagy inhibitor liensinine sensitizes breast cancer cells to chemotherapy through DNM1L-mediated mitochondrial fission. Autophagy. 2015;11(8):1259-79. DOI:10.1080/15548627.2015.1056970
Spectrum DetailBack Directory
[Spectrum Detail]

Liensinine diperchlorate(5088-90-4)1HNMR
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