| Identification | Back Directory | [Name]
VERPROSIDE | [CAS]
50932-20-2 | [Synonyms]
VERPROSIDE
VERPROSIDE USP/EP/BP
Verproside >=95% (LC/MS-ELSD)
[(1aS)-1a,1bα,2,5aα,6,6aβ-Hexahydro-6α-[(3,4-dihydroxybenzoyl)oxy]-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2α-yl]β-D-glucopyranoside
β-D-Glucopyranoside, (1aS,1bS,2S,5aR,6S,6aS)-6-[(3,4-dihydroxybenzoyl)oxy]-1a,1b,2,5a,6,6a-hexahydro-1a-(hydroxymethyl)oxireno[4,5]cyclopenta[1,2-c]pyran-2-yl | [Molecular Formula]
C22H26O13 | [MDL Number]
MFCD02259447 | [MOL File]
50932-20-2.mol | [Molecular Weight]
498.43 |
| Chemical Properties | Back Directory | [Boiling point ]
822.9±65.0 °C(Predicted) | [density ]
1.75±0.1 g/cm3(Predicted) | [storage temp. ]
-20°C | [form ]
solid | [pka]
7.90±0.20(Predicted) | [Major Application]
metabolomics
vitamins, nutraceuticals, and natural products | [InChIKey]
DBUOUVZMYWYRRI-YWEKDMGLSA-N | [SMILES]
OC[C@H]1O[C@@H](O[C@@H]2OC=C[C@H]3[C@H](OC(=O)c4ccc(O)c(O)c4)[C@@H]5O[C@]5(CO)[C@@H]23)[C@H](O)[C@@H](O)[C@@H]1O |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H319 | [Precautionary statements ]
P305+P351+P338 | [Hazard Codes ]
Xi | [Risk Statements ]
36 | [Safety Statements ]
26 | [WGK Germany ]
3 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Eye Irrit. 2 |
| Hazard Information | Back Directory | [Uses]
Verproside has been shown to inhibit TNF-α-induced MUC5AC expression which aids in preventing oversecretion of mucus in asthma and chronic obstructive pulmonary disease patients. | [Definition]
ChEBI: Verproside is a glycoside. It has a role as a metabolite. | [in vivo]
Verproside (Intragastrically; 30 mg/kg; 48 hours) significantly reduces the immunoglobulin E (IgE) levels of verproside-treated mice[2]. | Animal Model: | Specific pathogen-free female BALB/c mice aged 8-10 weeks[2] | | Dosage: | 30 mg/kg | | Administration: | Intragastrically; 48 hours | | Result: | Reduced significantly the immunoglobulin E (IgE) levels.
|
| [IC 50]
NF-κB; IKK |
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
| Company Name: |
Carbosynth
|
| Tel: |
+86 512 6260 5585 |
| Website: |
www.carbosynth.com |
|