| Identification | Back Directory | [Name]
ANTIBIOTIC MYC-8003 | [CAS]
50935-71-2 | [Synonyms]
myc8003
MOCIMYCIN
delvomycin
KIRROMYCIN
NSC 316094
ANTIBIOTIC MYC-8003
Antibiotic Myc-8003, Mocimycin
kirromycin from streptomyces collinus
Stereoisomer of N-[7-[5-[7-(1,2-dihydro-4-hydroxy-2-oxo-3-pyridinyl)-6-methyl-7-oxo-1,3,5-heptatrienyl]tetrahydro-3,4-dihydroxy-2-furanyl]-6-methoxy-5-methyl-2,4-octadienyl]-alpha-ethyltetrahydro-2,3,4-trihydroxy-5,5-dimethyl-6-(1,3-pentadienyl)-2H-pyran-2-acetamide
2H-Pyran-2-acetamide, N-[(2E,4E,6S,7R)-7-[(2S,3S,4R,5R)-5-[(1E,3E,5E)-7-(1,2-dihydro-4-hydroxy-2-oxo-3-pyridinyl)-6-methyl-7-oxo-1,3,5-heptatrien-1-yl]tetrahydro-3,4-dihydroxy-2-furanyl]-6-methoxy-5-methyl-2,4-octadien-1-yl]-α-ethyltetrahydro-2,3,4-trihydroxy-5,5-dimethyl-6-(1E,3Z)-1,3-pentadien-1-y... | [EINECS(EC#)]
256-859-9 | [Molecular Formula]
C43H60N2O12 | [MDL Number]
MFCD00467139 | [MOL File]
50935-71-2.mol | [Molecular Weight]
796.94 |
| Chemical Properties | Back Directory | [alpha ]
D22 -60° (c = 1 in methanol) | [storage temp. ]
−20°C
| [solubility ]
methanol: soluble1.90-2.10mg/mL, clear, yellow | [form ]
A solid | [color ]
yellow |
| Hazard Information | Back Directory | [Description]
Kirromycin is an antibiotic originally isolated from Streptomyces and an inhibitor of protein biosynthesis. It inhibits isoleucine incorporation, polyphenylalanine synthesis, and growth of B. brevis. Kirromycin inhibits elongation factor Tu-dependent peptidyl transfer activity in E. coli. | [Uses]
Kirromycin from Streptomyces collinus is an antibiotic inhibitor of protein synthesis. | [Definition]
ChEBI: Mocimycin is a C-glycosyl compound. | [storage]
Store at -20°C |
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