| Identification | Back Directory | [Name]
Dibenamine | [CAS]
51-50-3 | [Synonyms]
SKF 199
Dibenamine
(2-Chloroethyl)dibenzylamine
N,N-dibenzyl-2-chloroethanamine
bis(benzyl)-(2-chloroethyl)amine
N,N-Dibenzyl-2-chloroethan-1-amine
2-chloro-N,N-bis(phenylmethyl)ethanamine
Benzenemethanamine, N-(2-chloroethyl)-N-(phenylmethyl)- | [Molecular Formula]
C16H18ClN | [MOL File]
51-50-3.mol | [Molecular Weight]
259.77 |
| Chemical Properties | Back Directory | [Melting point ]
192 °C | [Boiling point ]
407.11°C (rough estimate) | [density ]
1.0738 (rough estimate) | [refractive index ]
1.6000 (estimate) | [pka]
6.50±0.50(Predicted) |
| Safety Data | Back Directory | [Safety Profile]
Poison by intravenous
and intraperitoneal routes. Moderately toxic
by ingestion and subcutaneous routes.
Experimental reproductive effects. Can
cause leukopenia (reduced whte blood cell
count). Mutation data reported. When
heated to decomposition it emits very toxic
fumes of Cl and NOx. See also
AROMATIC MINES. | [Hazardous Substances Data]
51-50-3(Hazardous Substances Data) |
| Hazard Information | Back Directory | [Uses]
Dibenamine is an alpha-adrenergic antagonist that exhibits the ability to block both basal and histamine-stimulated gastric acid secretion, making it therapeutically relevant in conditions involving excessive gastric acid production. | [References]
[1] The affinity and selectivity of α-adrenoceptor antagonists, antidepressants, and antipsychotics for the human α1A, α1B, and α1D-adrenoceptors DOI:10.1002/prp2.602 |
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