| Identification | Back Directory | [Name]
DIHYDROERGOTAMINE | [CAS]
511-12-6 | [Synonyms]
DIHYDROERGOTAMINE
9,10-Dihydroergotamine
Dihydroergotamine (base and/or unspecified salts)
9,10α-Dihydro-12'-hydroxy-2'-methyl-5'α-(phenylmethyl)ergotaman-3',6',18-trione | [EINECS(EC#)]
208-123-3 | [Molecular Formula]
C33H37N5O5 | [MDL Number]
MFCD00215847 | [MOL File]
511-12-6.mol | [Molecular Weight]
583.68 |
| Chemical Properties | Back Directory | [Melting point ]
239° | [alpha ]
D20 -64°; 20546 -79° (c = 0.5 in pyridine) | [Boiling point ]
641.14°C (rough estimate) | [density ]
1.1992 (rough estimate) | [refractive index ]
1.7500 (estimate) | [pka]
9≅+-.0.60(Predicted) |
| Hazard Information | Back Directory | [Definition]
ChEBI: Ergotamine in which a single bond replaces the double bond between positions 9 and 10. A semisynthetic ergot alkaloid with weaker oxytocic and vasoconstrictor properties than ergotamine, it is used (as the methanesulfonic or tartaric acid salts) for the tr
atment of migraine and orthostatic hypotension. | [Uses]
Anti-adrenergic. | [Uses]
Levadex is an intermediate in the synthesis of 2’-Epidihydroergotamine (E584910), which is an ergot alkaloid that exhibits potential neuroprotective properties against degenerative diseases. | [Brand name]
D.H.E. 45 (Valeant); Migranal (Valeant)
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