| Identification | Back Directory | [Name]
Clanfenur | [CAS]
51213-99-1 | [Synonyms]
Clanfenur
N-[[(4-chlorophenyl)amino]carbonyl]-2-(dimethylamino)-6-fluorobenzamide
Benzamide,N-[[(4-chlorophenyl)amino]carbonyl]-2-(dimethylamino)-6-fluoro- | [Molecular Formula]
C16H15ClFN3O2 | [MOL File]
51213-99-1.mol | [Molecular Weight]
335.76 |
| Chemical Properties | Back Directory | [density ]
1.371±0.06 g/cm3(Predicted) | [solubility ]
Acetonitrile: Slightly soluble: 0.1-1 mg/mL
DMSO: Sparingly soluble: 1-10 mg/mL | [form ]
Solid | [pka]
9.37±0.46(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
Clanfenur is a substituted benzoylphenylurea, an analogue of the pesticide fenfluramide, with potential antineoplastic activity. Clanfenur can bind to the colchicine-binding site on β-tubulin, inhibit microtubule polymerization, and thus prevent tumor cell replication[1]. | [References]
[1] J D Jonkman-de Vries, et al. Pharmaceutical development of a parenteral formulation of the investigational anticancer drug clanfenur. PDA J Pharm Sci Technol. 1997 Mar-Apr;51(2):89-95. PMID:9146040 |
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BOC Sciences
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https://www.bocsci.com |
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InvivoChem
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13549236410 |
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https://www.invivochem.cn/ |
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