ChemicalBook--->CAS DataBase List--->51246-79-8

51246-79-8

51246-79-8 Structure

51246-79-8 Structure
IdentificationBack Directory
[Name]

2',3'-dideoxy-3'-fluorocytidine
[CAS]

51246-79-8
[Synonyms]

Fddcyd
3'-Fddc
Aids000014
Aids-000014
3'-Fluoro-2',3'-dideoxycytidine
2',3'-dideoxy-3'-fluorocytidine
2',3'-Dideoxy-3'-fluorocytidine
Cytidine, 2',3'-dideoxy-3'-fluoro-
2’,3’-Dideoxy-3’-fluorocytidine, FddC
2’,3’-Dideoxy-3’-fluorocytidine, FddC, HIV-1 inhibitor
1-(3-fluoro-2,3-dideoxy-β-D-erythro-pentofuranosyl)cytosine
[Molecular Formula]

C9H12FN3O3
[MOL File]

51246-79-8.mol
[Molecular Weight]

229.21
Chemical PropertiesBack Directory
[Boiling point ]

418.0±55.0 °C(Predicted)
[density ]

1.67±0.1 g/cm3(Predicted)
[form ]

Solid
[pka]

14.44±0.10(Predicted)
[color ]

Off-white to light yellow
Hazard InformationBack Directory
[Uses]

2’,3’-Dideoxy-3’-fluorocytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
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