| Identification | Back Directory | [Name]
1H-Benzimidazol-2-amine,N-butyl-(9CI) | [CAS]
51314-51-3 | [Synonyms]
NSC 139486
1H-Benzimidazol-2-amine, N-butyl-
N-Butyl-1H-benzo[d]iMidazol-2-aMine
1H-Benzimidazol-2-amine,N-butyl-(9CI) | [Molecular Formula]
C11H15N3 | [MDL Number]
MFCD06370771 | [MOL File]
51314-51-3.mol | [Molecular Weight]
189.26 |
| Chemical Properties | Back Directory | [Melting point ]
155 °C | [Boiling point ]
344.8±25.0 °C(Predicted) | [density ]
1.153±0.06 g/cm3(Predicted) | [storage temp. ]
2-8°C | [form ]
Solid | [pka]
11.50±0.10(Predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Uses]
M084 is a benzimidazole derivative. M084 inhibits the mitochondrial respiration, activate mitochondrial unfolded protein response and AMPK, recruites SIR-2.1 and SKN-1, and finally through the transcription factor DAF-16, delays the aging process of C. elegans[1]. | [Definition]
ChEBI: N-butyl-1H-benzimidazol-2-amine is a member of benzimidazoles. | [References]
[1] Ai-Jun Ding, et al. Benzimidazole derivative M084 extends the lifespan of Caenorhabditis elegans in a DAF-16/FOXO-dependent way. Mol Cell Biochem. 2017 Feb;426(1-2):101-109. DOI:10.1007/s11010-016-2884-x |
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