| Identification | Back Directory | [Name]
4-AMINO-CYCLOHEXANECARBOXYLIC ACID ETHYL ESTER | [CAS]
51498-33-0 | [Synonyms]
Ethyl 4-aMinocyclohexanecarboxylate
4-AMINO-CYCLOHEXANECARBOXYLIC ACID ETHYL ESTER
Cyclohexanecarboxylic acid, 4-aMino-, ethyl ester | [Molecular Formula]
C9H17NO2 | [MDL Number]
MFCD01995051 | [MOL File]
51498-33-0.mol | [Molecular Weight]
171.24 |
| Chemical Properties | Back Directory | [Boiling point ]
114-117 °C(Press: 10 Torr) | [density ]
1.018±0.06 g/cm3(Predicted) | [storage temp. ]
under inert gas (nitrogen or Argon) at 2–8 °C | [pka]
10.36±0.70(Predicted) |
| Hazard Information | Back Directory | [Synthesis]
GENERAL STEPS: 4-Aminocyclohexanecarboxylic acid (5.0 g, 34.92 mmol) was dissolved in ethanol (20 mL) and cooled to 0 °C. Thionyl chloride (7.60 mL, 104.76 mmol) was slowly added dropwise with stirring. After the dropwise addition, the reaction mixture was heated to 80 °C and maintained for 2-3 hours. The reaction process was monitored by thin layer chromatography (TLC). After completion of the reaction, the solvent was removed by evaporation under reduced pressure to give ethyl 4-aminocyclohexane-1-carboxylate in quantitative yield. | [References]
[1] Patent: US2012/88750, 2012, A1. Location in patent: Page/Page column 41
[2] Patent: WO2006/77424, 2006, A1. Location in patent: Page/Page column 162-163
[3] Patent: WO2006/77425, 2006, A1. Location in patent: Page/Page column 162-163
[4] Patent: WO2006/77428, 2006, A1. Location in patent: Page/Page column 140
[5] Patent: US2013/252938, 2013, A1. Location in patent: Paragraph 0502 |
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| Company Name: |
SynAsst Chemical.
|
| Tel: |
021-60343070 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15848/0_EN.htm |
| Company Name: |
NovoChemy Ltd.
|
| Tel: |
86-(0)21-31261262 373522135 |
| Website: |
www.novochemy.com |
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