| Identification | Back Directory | [Name]
(2-PHENOXY)METHYLSULFONYLANILINE | [CAS]
51765-51-6 | [Synonyms]
Einecs 257-399-1
Nimesulide impurity-B(EP/BP)
2-PHENOXYMETHANESULFOANILIDE
2-Phenoxymethanesulfonailide
2-PHENOXYMETHANESULFONANILIDE
(2-PHENOXY)METHYLSULFONYLANILINE
N-(2-Phenoxyphenyl)methanesulphonam
2 - phenoxy-methane-sulfonyl aniline
N-(2-phenoxyphenyl)methanesulphonamide
Methanesulfonamide, N-(2-phenoxyphenyl)-
Nimesulide EP Impurity B,(N-（2-phenoxyphenyl)methanesulfonamide) | [EINECS(EC#)]
257-399-1 | [Molecular Formula]
C13H13NO3S | [MDL Number]
MFCD03389778 | [MOL File]
51765-51-6.mol | [Molecular Weight]
263.31 |
| Chemical Properties | Back Directory | [Melting point ]
126℃ | [Boiling point ]
378.9±44.0 °C(Predicted) | [density ]
1.313 | [vapor pressure ]
0Pa at 25℃ | [storage temp. ]
Keep in dark place,Inert atmosphere,Room temperature | [solubility ]
Chloroform (Slightly), DMSO | [form ]
Solid | [pka]
8.43±0.10(Predicted) | [color ]
White to Off-White | [Water Solubility ]
176.1mg/L at 25℃ | [LogP]
2.4 at 25℃ |
| Hazard Information | Back Directory | [Uses]
2''-Phenoxymethanesulfonanilide is a metabolite of nimesulide (N477500), which is an antiinflammatory agent. It preferentially inhibits COX-2 over COX-1 and suppresses chemical-induced carcinogenesis in mice and rats. Nimesulide also nhibits LPS-induced TNF-alpha production. |
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