ChemicalBook--->CAS DataBase List--->51766-21-3

51766-21-3

51766-21-3 Structure

51766-21-3 Structure
IdentificationBack Directory
[Name]

PHENYL N-PHENYLPHOSPHORAMIDOCHLORIDATE
[CAS]

51766-21-3
[Synonyms]

3P-CL
TIMTEC-BB SBB003052
Phenyl phenylphosphoraMidochloridate
PHENYL N-PHENYL-CHLORO-PHOSPHORAMIDATE
PHENYL N-PHENYLPHOSPHORAMIDOCHLORIDATE
O-Phenyl N-phenylphosphoramidochloridate
N-Phenylphosphoramidochloridic acid phenyl
PHENYL N-PHENYLPHOSPHORAMIDOCHLORIDATE, 99%+
Phenylphosphoramidochloridic acid phenyl ester
N-Phenylamidochloridophosphoric acid phenyl ester
[EINECS(EC#)]

257-400-5
[Molecular Formula]

C12H11ClNO2P
[MDL Number]

MFCD00003029
[MOL File]

51766-21-3.mol
[Molecular Weight]

267.65
Chemical PropertiesBack Directory
[Appearance]

white powder
[Melting point ]

132-134 °C(lit.)
[Boiling point ]

366℃
[density ]

1.363
[Fp ]

175℃
[storage temp. ]

Store at room temperature
[solubility ]

sol org solvents, e.g. acetone, dichloromethane.
[form ]

solid
[color ]

white
Hazard InformationBack Directory
[Chemical Properties]

white powder
[Uses]

Phenyl N-Phenylphosphoramidochloridate is a phosphorylating agent in oligonucleotide synthesis via the phosphotriester approach; for the conversion of acids to their symmetrical anhydrides and for the coupling of acids and amines to give amides; two important derivatives are also considered.
[Preparation]

Phenyl N-Phenylphosphoramidochloridate is obtained from phenyl phosphorodichloridate (2) and aniline (eq 1).[1]
PHENYL N-PHENYLPHOSPHORAMIDOCHLORIDATE synthesis
[storage]

Phenyl N-Phenylphosphoramidochloridate is irritating and moisture-sensitive. It may be harmful by inhalation (irritating to mucous membranes and upper respiratory tract), ingestion, or skin absorption. Incompatible with strong oxidizing agents and strong bases.
[References]

1. Cremlyn, R. W. J.; Kishore, D. N. JCS(P1) 1972, 585.
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

26-36
[WGK Germany ]

3
[HS Code ]

29310099
Spectrum DetailBack Directory
[Spectrum Detail]

PHENYL N-PHENYLPHOSPHORAMIDOCHLORIDATE(51766-21-3)1HNMR
PHENYL N-PHENYLPHOSPHORAMIDOCHLORIDATE(51766-21-3)13CNMR
PHENYL N-PHENYLPHOSPHORAMIDOCHLORIDATE(51766-21-3)IR1
PHENYL N-PHENYLPHOSPHORAMIDOCHLORIDATE(51766-21-3)Raman
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