| Identification | Back Directory | [Name]
(3S,6S,7R,8R)-8-benzyl-3-{[(4-methoxy-3-{[(2-methylpropanoyl)oxy]methoxy}pyridin-2-yl)carbonyl]amino}-6-methyl-4,9-dioxo-1,5-dioxonan-7-yl 2-methylpropanoate | [CAS]
517875-34-2 | [Synonyms]
XDE777 XDE-777 XDE 777 (3S,6S,7R,8R)-8-benzyl-3-{[(4-methoxy-3-{[(2-methylpropanoyl)oxy]methoxy}pyridin-2-yl)carbonyl]amino}-6-methyl-4,9-dioxo-1,5-dioxonan-7-yl 2-methylpropanoate Propanoic acid, 2-methyl-, [[4-methoxy-2-[[[(3S,7R,8R,9S)-9-methyl-8-(2-methyl-1-oxopropoxy)-2,6-dioxo-7-(phenylmethyl)-1,5-dioxonan-3-yl]amino]carbonyl]-3-pyridinyl]oxy]methyl ester | [EINECS(EC#)]
815-084-1 | [Molecular Formula]
C31H38N2O11 | [MDL Number]
MFCD31716173 | [MOL File]
517875-34-2.mol | [Molecular Weight]
614.64 |
| Hazard Information | Back Directory | [Description]
A novel antibiotic fungicide with a new class of chemistry. It has a low human health risk with no major concerns being identified in the initial data set. It appears to degrade quickly in soils and is unstable in water. It also has a low toxicity to birds but is a much higher risk to aquatic organisms. | [Uses]
Fenpicoxamid-D3 is a labelled analogue of Fenpicoxamid (F628980), which is used as a fungicide for cereals and other crops. It is also a pesticide/antibiotic. | [Definition]
ChEBI: Fenpicoxamid is a carboxamide resulting from the formal condensation of the carboxy group of 3-[(isobutyryloxy)methoxy]-4-methoxypyridine-2-carboxylic acid with the amino group of (3S,6S,7R,8R)-3-amino-8-benzyl-6-methyl-4,9-dioxo-1,5-dioxonan-7-yl 2-methylpropanoate. Introduced by Dow AgroSciences, it is an antibiotic fungicide with a new target site for disease control in Septoria species. It has a role as an agrochemical. It is an antibiotic fungicide, a member of pyridines, a lactone, an acetal and a secondary carboxamide. | [Production Methods]
Fenpicoxamid is manufactured by first fermenting the producing microorganism to obtain UK 2A, then chemically modifying the natural macrocyclic core to generate a more stable, field active fungicide. The key commercial step is the acylation of the UK 2A hydroxyl group to form the picolinamide ester, which defines fenpicoxamid, improving stability and enabling formulation. This process results in a novel antibiotic fungicide with a new class of chemistry, offering a new site of action for broad spectrum disease control in cereals | [Mechanism of action]
A QiI fungicide that acts at the quinone inside (Qi) site of the inner membrane of complex III | [Pesticide Type]
Fungicide |
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