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Urease-IN-11 (Compound 6e) is a competitive urease inhibitor (IC50)=10.41 μM). Urease-IN-11 can be used to study diseases such as urease-related gastritis and peptic ulcer[1]. | [References]
[1] Ullah S, et al. Urease inhibitory potential of pyridine-containing triazolothiadiazole and triazolothiadiazine scaffolds for the treatment of ulceration and kidney stone: in vitro screening, kinetics mechanism, and in silico computational analysis. J Biomol Struct Dyn. 2023 Dec 28:1-10. DOI:10.1080/07391102.2023.2291542 |
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