| Identification | Back Directory | [Name]
3-(4-methoxyphenyl)-6-(4-phenylphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine | [CAS]
517906-16-0 | [Synonyms]
Urease-IN-8
3-(4-methoxyphenyl)-6-(4-phenylphenyl)-7H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazine
7H-1,2,4-Triazolo[3,4-b][1,3,4]thiadiazine, 6-[1,1'-biphenyl]-4-yl-3-(4-methoxyphenyl)- | [Molecular Formula]
C23H18N4OS | [MOL File]
517906-16-0.mol | [Molecular Weight]
398.48 |
| Hazard Information | Back Directory | [Uses]
Urease-IN-8 (Compound 5e) is a competitive Urease inhibitor (IC50: 3.51 μM, Ki: 3.11 μM). Urease-IN-8 can be used for research of peptic and gastric ulcers[1]. | [References]
[1] Jalal Uddin, et al. Triazolothiadiazoles and Triazolothiadiazines as New and Potent Urease Inhibitors: Insights from In Vitro Assay, Kinetics Data, and In Silico Assessment. ACS Omega 2023, 8, 35, 31890 1898. |
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