| Identification | Back Directory | [Name]
ambucetamide | [CAS]
519-88-0 | [Synonyms]
Bersen
Meritin
Dibutamid
Dibutamide
Ambucetamid
ambucetamide
a-(Dibutylamino)-4-methoxy-benzeneacetamide
Benzeneacetamide, α-(dibutylamino)-4-methoxy-
2-(dibutylamino)-2-(4-methoxyphenyl)acetamide
2-(dibutylamino)-2-(4-methoxyphenyl)ethanamide | [EINECS(EC#)]
208-278-7 | [Molecular Formula]
C17H28N2O2 | [MDL Number]
MFCD00865229 | [MOL File]
519-88-0.mol | [Molecular Weight]
292.42 |
| Chemical Properties | Back Directory | [Melting point ]
134°; first reported as mp 125-127° | [Boiling point ]
434.34°C (rough estimate) | [density ]
0.9876 (rough estimate) | [refractive index ]
1.5800 (estimate) | [storage temp. ]
-20°C Freezer | [solubility ]
DMSO (Slightly), Ethyl Acetate (Slightly, Sonicated), Methanol (Slightly) | [form ]
Solid | [pka]
15.81±0.50(Predicted) | [color ]
White to Pale Yellow |
| Hazard Information | Back Directory | [Uses]
Ambucetamide is an antispasmodic found to be particularly effective for the relief of menstrual pain. | [Definition]
ChEBI: Ambucetamide is an amino acid amide. | [in vivo]
Ambucetamide (0-30 mg/kg, jugular vein injection) decreases in the amplitude and frequency of contractions in rat-uterine[2].
Ambucetamide (1-10 mg/kg, femoral vein injection) reduces the tone of the uterus and increased the amplitude of contractions in dogs[2].
| Animal Model: | Dogs[2] | | Dosage: | 1-10 mg/kg | | Administration: | Femoral vein injection | | Result: | Showed a decrease in the amplitude of contractions at 10 mg/kg. |
| [Purification Methods]
Crystallise ambucetamide from EtOH containing 10% diethyl ether. [Janssen J Am Chem Soc 76 6192 1954, Beilstein 14 IV 2101.] |
|
| Company Name: |
Energy Chemical
|
| Tel: |
021-58432009 400-005-6266 |
| Website: |
http://www.energy-chemical.com |
|