| Identification | Back Directory | [Name]
ethyl trans-2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate | [CAS]
51931-66-9 | [Synonyms]
Dea no. 9750
Tilidate [ban]
trans-Tilidine
Einecs 257-522-9
ethyl trans-2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate
Ethyl trans-2-(dimethylamino)-1-phenyl-3-cyclohexene-1-carboxylate
3-Cyclohexene-1-carboxylic acid, 2-(dimethylamino)-1-phenyl-, ethyl ester, trans-
3-Cyclohexene-1-carboxylic acid, 2-(dimethylamino)-1-phenyl-, ethyl ester, (1R,2S)-rel- | [EINECS(EC#)]
257-522-9 | [Molecular Formula]
C17H23NO2 | [MOL File]
51931-66-9.mol | [Molecular Weight]
273.37 |
| Hazard Information | Back Directory | [Uses]
Tilidine is an opioid used primarily as a painkiller it inhibits the enzyme adenylyl cyclase. | [Definition]
ChEBI: Dextilidine is an ethyl 2-(dimethylamino)-1-phenylcyclohex-3-ene-1-carboxylate that has S configuration at the carbon bearing the phenyl group and R configuration at the carbon bearing the dimethylamino group. The opioid analgesic tilidine is the racemate comprising equimolar amounts of dextilidine and its enantiomer, ent-dextilidine. A prodrug, tilidine is converted by the liver to the active analgesic, nortilidine; virtually all of the opioid activity resides in the (1S,2R) isomer (i.e. the isomer derived from dextilidine). It has a role as an opioid analgesic and a prodrug. It is an enantiomer of an ent-dextilidine. |
|