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52037-90-8

52037-90-8 Structure

52037-90-8 Structure
IdentificationBack Directory
[Name]

CYCLOHEXANONE MONOOXYGENASE F. ACINETO-B ACTER SP., ~5 U/G
[CAS]

52037-90-8
[Synonyms]

cyclohexanone monooxygenase
Cyclohexanone Monooxygenase from Xanthobacter sp.
Cyclohexanone Monooxygenase from Acinetobacter sp.
Cyclohexanone Monooxygenase from Nocardia globerula
CYCLOHEXANONE MONOOXYGENASE F. NOCARDIA GLOBERULA, ~4 U/G
CYCLOHEXANONE MONOOXYGENASE F. ACINETO-B ACTER SP., ~5 U/G
CYCLOHEXANONE MONOOXYGENASE FROM XANTHO- BACTER SP., ~6 U/G
CYCLOHEXANONE MONOOXYGENASE ACINETOBACTER SP., REC. ~12U/ML*
Cyclohexanone Monooxygenase from Acinetobacter sp., Recombinant
Cyclohexanone Monooxygenase from Acinetobacter sp. >=12 U/mL, ammonium sulfate suspension, recombinant, expressed in E. coli
[MDL Number]

MFCD00146601
Chemical PropertiesBack Directory
[Melting point ]

35-36.5 °C
[storage temp. ]

−20°C
[form ]

powder
[color ]

off-white
Safety DataBack Directory
[WGK Germany ]

3
[F ]

3-10-21
[Storage Class]

11 - Combustible Solids
[Hazard Classifications]

Resp. Sens. 1
Hazard InformationBack Directory
[Uses]

Cyclohexanone monooxygenase has been used in a study th at cloned and overexpressed the 2-oxo-Δ(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase (OTEMO) in Escherichia coli. Cyclohexanone monooxygenase has also been used in a study th at investigated the effects of structural modification of the cell wall on the biotransformation capability by recombinant Corynebacterium glutamicum cells.
[Biological Activity]

Purified cyclohexanone monooxygenase has a molecular weight of 59,000 Da. It is a versatile oxygenation catalyst. The enzyme uses the bound FAD-4a-OOH oxygenating intermediate to initiate transfer of oxygen to electrophilic substrate sites. The reaction consequently yields the corresponding sulfoxide and selenoxide products. This enzyme is also capable of oxygenating at nitrogentrivalent phosphorusand boron sites in boronic acids. Henceit is one of the most broad-based flavoprotein oxygenases known.
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