| Identification | Back Directory | [Name]
Benzo[c]phenanthridinium, 2-hydroxy-3,8,9-trimethoxy-5-methyl-, chloride (9CI) (MF1) | [CAS]
52259-64-0 | [Synonyms]
NSC157995
NSC-157995
NSC 157995
Benzo[c]phenanthridinium, 2-hydroxy-3,8,9-trimethoxy-5-methyl-, chloride (9CI) (MF1) | [Molecular Formula]
C21H20ClNO4 | [MOL File]
52259-64-0.mol | [Molecular Weight]
385.841 |
| Hazard Information | Back Directory | [Uses]
Fagaronine chloride is an alkaloid with inhibitory activity against reverse transcriptase and topoisomerase I. Fagaronine chloride can effectively inhibit the reverse transcriptase of RSii tumor virus at a concentration of 6-60 μg/mL. Fagaronine chloride rapidly blocks the synthesis of DNA polymerase by interacting with the template primer. Fagaronine chloride has shown anti-tumor potential, especially in the study of retroviral infection[1]. | [References]
[1] INHIBITION OF RET'ERSE TRANSCRIPTASE ACTII'ITY BY BENZOPHENASTHRIDINE ALKALOIDS |
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