| Identification | Back Directory | [Name]
Etybenzatropine | [CAS]
524-83-4 | [Synonyms]
UK-738
VK-738
Ponalide
Etybenzatropine
ethybenztropine
Etibenzatropina
Ethylbenatropine
Ethylbenztropine
Etybenzatropine USP/EP/BP
8-Azabicyclo[3.2.1]octane, 3-(diphenylmethoxy)-8-ethyl-, (3-endo)- | [Molecular Formula]
C22H27NO | [MDL Number]
MFCD00865155 | [MOL File]
524-83-4.mol | [Molecular Weight]
321.461 |
| Hazard Information | Back Directory | [Uses]
Anticholinergic. | [Definition]
ChEBI: Etybenzatropine is a diarylmethane. | [Brand name]
Panolid (Novartis). | [in vivo]
Ethybenztropine (25 μg, microinjected into mesencephalic NRM) blocks the hypertherrnic response of carbachol microinjection into nucleus raphe median (NRM) of rabbits[1].
Ethybenztropine (30-60 μg/kg, administered by the fourth ventricle) is effective in preventing arrhythmias in dogs[2].
Ethybenztropine (50 mg/kg, i.p.) reduces the catecholamines accumulation in rats[3].
| Animal Model: | Dogs with cardiac arrhythmias[2] | | Dosage: | 30-60 μg/kg | | Administration: | Administered by the fourth ventricle | | Result: | Produced slight hypotension (never exceeding a fall of 25 mm Hg) and slight sinus tachycardia.
Converted arrhythmias to sinus rhythms.
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