| Identification | Back Directory | [Name]
1-(-D-Xylofuranosyl)-5-methyluracil | [CAS]
52486-19-8 | [Synonyms]
Xylo-5-methyluridine
1-(-D-Xylofuranosyl)-5-methyluracil
1-(b-D-Xylofuranosyl)-5-methyluracil
1-(beta-D-Xylofuranosyl)-5-methyluracil
2,4(1H,3H)-Pyrimidinedione, 5-methyl-1-β-D-xylofuranosyl- | [Molecular Formula]
C10H14N2O6 | [MOL File]
52486-19-8.mol | [Molecular Weight]
258.228 |
| Hazard Information | Back Directory | [Uses]
1-(β-D-Xylofuranosyl)-5-methyluracil is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1]. | [References]
[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
[2] Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93. DOI:10.3390/molecules16097980 |
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