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52486-19-8

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52486-19-8 Structure

52486-19-8 Structure
IdentificationBack Directory
[Name]

1-(-D-Xylofuranosyl)-5-methyluracil
[CAS]

52486-19-8
[Synonyms]

Xylo-5-methyluridine
1-(-D-Xylofuranosyl)-5-methyluracil
1-(b-D-Xylofuranosyl)-5-methyluracil
1-(beta-D-Xylofuranosyl)-5-methyluracil
2,4(1H,3H)-Pyrimidinedione, 5-methyl-1-β-D-xylofuranosyl-
[Molecular Formula]

C10H14N2O6
[MOL File]

52486-19-8.mol
[Molecular Weight]

258.228
Chemical PropertiesBack Directory
[Melting point ]

156-157.5 °C(Solv: ethanol (64-17-5))
[density ]

1.576±0.06 g/cm3(Predicted)
[pka]

9.55±0.10(Predicted)
Hazard InformationBack Directory
[Uses]

1-(β-D-Xylofuranosyl)-5-methyluracil is a thymidine analog. Analogs of this series have insertional activity towards replicated DNA. They can be used to label cells and track DNA synthesis[1].
[References]

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
[2] Cavanagh BL, et al. Thymidine analogues for tracking DNA synthesis. Molecules. 2011 Sep 15;16(9):7980-93. DOI:10.3390/molecules16097980
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