52510-53-9

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52510-53-9 Structure

Identification	Back Directory
[Name] tetranor-PGAM
[CAS] 52510-53-9
[Synonyms] tetranor-PGAM tetranor-PGAM Exclusive HYPIFMOQVFWSBF-WCQYABFASA-N tetranor-prostaglandin A metabolite 2-Cyclopentene-1-octanoic acid, 5-(2-carboxyethyl)-ε,4-dioxo-, (1S,5R)-
[Molecular Formula] C16H22O6
[MOL File] 52510-53-9.mol
[Molecular Weight] 310.35

Chemical Properties	Back Directory
[storage temp. ] Store at -20°C
[solubility ] DMF: 50 mg/ml; DMSO: 50 mg/ml; Ethanol: 50 mg/ml; PBS (pH 7.2): 1 mg/ml

Safety Data	Back Directory
[Symbol(GHS) ] GHS02,GHS07
[Signal word ] Danger
[Hazard statements ] H225-H319-H336
[Precautionary statements ] P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501

Hazard Information	Back Directory
[Description] Prostaglandin E₂ (PGE₂), one of the most widely investigated PGs, can be used as a biomarker of inflammation, disease state, or therapeutic effectiveness. However due to its rapid metabolism, direct measurement of PGE₂ in biological samples is difficult. The major urinary metabolite of PGE₂, tetranor-PGEM, serves as an indirect marker of PGE₂ biosynthesis. Though like PGE₂, tetranor-PGEM is also chemically unstable. tetranor-PGAM is a dehydration product of tetranor-PGEM and can be measured as a surrogate for tetranor-PGEM levels in urine.
[Definition] ChEBI: Tetranor-PGAM is an oxo carboxylic acid.

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