525596-66-1

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525596-66-1 Structure

Chemical Properties	Back Directory
[storage temp. ] Desiccate at RT
[solubility ] Soluble to 100 mM in water and to 100 mM in DMSO
[form ] Powder
[color ] Off-white to light yellow

Hazard Information	Back Directory
[Uses] bPiDDB is α7 nicotinic receptor antagonist.
[in vivo] bPiDDB (peripherally administered) inhibits nicotine-evoked dopamine (DA) release in nucleus accumbens and decrease intravenous nicotine self-administration in rats^[1]. bPiDDB is brain bioavailable following peripheral administration and is transported actively by the blood-brain barrier choline transporter into the central compartment^[1].
[storage] Desiccate at RT

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125652-55-3 67261-23-8 67261-31-8 67261-30-7 67261-22-7

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