| Identification | Back Directory | [Name]
hydroxyethyloxamic acid | [CAS]
5270-73-5 | [Synonyms]
hydroxyethyloxamic acid
N-(2-Hydroxyethyl)oxamic acid
Acetic acid, 2-[(2-hydroxyethyl)amino]-2-oxo- | [Molecular Formula]
C4H7NO4 | [MOL File]
5270-73-5.mol | [Molecular Weight]
133.1 |
| Hazard Information | Back Directory | [Uses]
N-(2-hydroxyethyl)-oxamic acid is formed when Metronidazole is reduced either chemically or by the action of the intestinal bacteria. Metronidazole, a nitroimidazole antibiotic, has activity against various protozoans and most Gram-negative and Gram-positive anaerobic bacteria[1][2]. | [References]
[1] Koch RL, et al. The anaerobic metabolism of metronidazole forms N-(2-hydroxyethyl)-oxamic acid. J Pharmacol Exp Ther. 1979;208(3):406-410. DOI:10.2165/00003495-199754050-00003
[2] Freeman CD, et al. Metronidazole. A therapeutic review and update. Drugs. 1997;54(5):679-708. DOI:10.2165/00003495-199754050-00003 |
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