| Identification | Back Directory | [Name]
α-1,4-Galactosyltransferase from Neisseria meningitides, Recombinant | [CAS]
52725-57-2 | [Synonyms]
α-1,4-Galactosyltransferase
lactosylceramide 4-α-galactosyltransferase
α-1,4-Galactosyltransferase from Neisseria meningitides, Recombinant |
| Hazard Information | Back Directory | [Uses]
alpha-1,4-Galactosyltransferase (LgtC) (A4GALT) is a glycosphingolipid-specific glycosyltransferase. alpha-1,4-Galactosyltransferase (LgtC) transfers a galactose to the alpha-1,4 position of lactosylceramide to form globotriaosylceramide. alpha-1,4-Galactosyltransferase (LgtC) can be used for the synthesis of P1 blood group antigens[1][2]. | [References]
[1] Kaczmarek R, et al. Evaluation of an amino acid residue critical for the specificity and activity of human Gb3/CD77 synthase. Glycoconj J. 2016 Dec;33(6):963-973. DOI:10.1007/s10719-016-9716-9
[2] Iwamura K, et al. The blood group P1 synthase gene is identical to the Gb3/CD77 synthase gene. A clue to the solution of the P1/P2/p puzzle. J Biol Chem. 2003 Nov 7;278(45):44429-38. DOI:10.1074/jbc.M301609200 |
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