52768-17-9

4533-42-0

52768-17-9

Under standard reaction conditions, 5.0 mg of Pd-gCN catalyst (containing 5.0 wt% Pd) was added to an ethanol solution (2 mL) containing 1.0 mM 1-(4-nitrophenyl)-1H-pyrrole, followed by the addition of 2 mM (1.2 eq., 0.07 mL) of 60% hydrazine hydrate solution. The reaction mixture was transferred to a 10 mL round bottom flask and reacted at reflux temperature (70 °C) for 4 hours. After completion of the reaction, the mixture was cooled to room temperature and the catalyst was isolated by filtration. The filtrate was purified by silica gel column chromatography to give 4-(1-pyrrolyl)aniline. For dinitroaromatic substrates, 4.0 mM (2.4 eq., 0.14 mL) of 60% hydrazine hydrate solution is required.